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DISTRIBUTION OF CYTOSIDERIN AND CYTOPLASMIC PARTICLES DEMONSTRATED BY OXIDATION-ALDEHYDE FUCHSIN PROCEDURES

S. S. SPICER 1

1 Laboratory of Experimental Pathology, NIAMD, National Institutes of Health, Bethesda 14, Maryland

Prussian blue-reactive particles, designated cytosiderin, have been demonstrated in various epithelia of rats, hamsters and guinea pigs retired from the breeding colony. Weanling animals lack such deposits. The distribution of cytosiderin in the various histologic sites differs for each species. Morphologically similar particles have been visualized by means of staining with oxidation-aldehyde fuchsin techniques. The latter cytoplasmic particles, present in the rodents examined as well as in human tissues, were encountered either in the same organs as those with cytosiderin or in organs lacking Prussian blue-reactive particles.

Submitted on January 15, 1962


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