Journal of Histochemistry and Cytochemistry Priciples for Free Access to Science
  Search:   
    >> Advanced Search

Guidelines | Subscriptions | About | exPRESS - Current - Archive | Business Information | Contact
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by GUNTHER, R. E.
Right arrow Articles by GLICK, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by GUNTHER, R. E.
Right arrow Articles by GLICK, D.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

DETERMINATION OF HISTAMINASE ACTIVITY IN HISTOLOGIC SAMPLES AND ITS QUANTITATIVE DISTRIBUTION IN INTACT HUMAN PLACENTA AND UTERUS

RONALD E. GUNTHER 1 and DAVID GLICK 1

1 Division of Histochemistry, Department of Pathology, Stanford University Medical School, Palo Alto, California

The spectrophotometric method for determination of histaminase, based on measurement of the hydrogen peroxide formed by the enzymatic oxidation of histamine, was modified and adapted to studies on microliter volumes of tissue (placenta) homogenates and microtome sections of tissue (human uterus and attached intact placenta at term). Optimal conditions for these assays were established. From analyses of tissue sections, peak enzyme activities were observed in the decidua, thus supporting the concept that this tissue is a significant source of the increased enzyme in blood plasma during pregnancy in the human. Inhibitor studies with aminoguanidine sulfate showed that the histaminase investigated in the human placenta was diamine oxidase. No histaminase activity was detected in isolated peritoneal mast cells from the rat or in homogenates of rat stomach mucosa.

Submitted on March 9, 1967


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 Hum Reprod UpdateHome page
L. Maintz, V. Schwarzer, T. Bieber, K. van der Ven, and N. Novak
Effects of histamine and diamine oxidase activities on pregnancy: a critical review
Hum. Reprod. Update, September 1, 2008; 14(5): 485 - 495.
[Abstract] [Full Text] [PDF]



Guidelines | Subscriptions | About | exPRESS - Current - Archive | Business Information | Contact
The Journal of Histochemistry & Cytochemistry is owned, published, and licensed by The Histochemical Society © 1967