Journal of Histochemistry and Cytochemistry Priciples for Free Access to Science
  Search:   
    >> Advanced Search

Guidelines | Subscriptions | About | exPRESS - Current - Archive | Business Information | Contact
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by CHANG, C.-H.
Right arrow Articles by GOLDFISCHER, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by CHANG, C.-H.
Right arrow Articles by GOLDFISCHER, S.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

SMALL CYTOPLASMIC BODIES IN THE LOOP OF HENLE AND DISTAL CONVOLUTED TUBULE THAT RESEMBLE PEROXISOMES

CHUNG-HO CHANG 1, BERNICE SCHILLER 1, and SIDNEY GOLDFISCHER 1

1 Department of Pathology, Albert Einstein College of Medicine, Yeshiva University, Bronx, New York 10461

Renal peroxisomes are believed to be restricted to the proximal convoluted tubules. However, we have found particles in the loop of Henle and distal convoluted tubule that resemble the peroxisomes of the proximal tubules in some respects. Although smaller in size (generally too small to be resolved in the light microscope), they have a finely granular homogenous matrix and are delimited by a single unit membrane. Whether these are microbodies (peroxisomes) or dense bodies (lysosomes) cannot be determined solely on the basis of their fine structure. These bodies do not show acid phosphatase activity, indicating that they are not lysosomes. When incubated in a diaminobenzidine medium that demonstrates the peroxidatic activity of the peroxisomal enzyme catalase, the small bodies are reactive, suggesting that they are peroxisomes. This activity is blocked by 3-amino-1,2,4-triazole, an inhibitor of catalase.

Submitted on June 3, 1970


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?





Guidelines | Subscriptions | About | exPRESS - Current - Archive | Business Information | Contact
The Journal of Histochemistry & Cytochemistry is owned, published, and licensed by The Histochemical Society © 1971