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Approach to three-dimensional mapping of quantitative histochemical measurements applied to studies of the cochlear nucleus

DA Godfrey and FM Matschinsky

After reviewing the historical development of some procedures for localizing quantitative histochemical measurements, an approach is presented which combines some aspects of these procedures to make possible a permanent, objective record of the location of each sample. The method further allows direct comparisons to be made with drawings of other nearby sections during the process of sampling. Illustrations are given of various applications to a study of the cochlear nucleus. A particular benefit of the approach is to facilitate comparison of chemical with anatomical and physiologic data.

Volume 24, Issue 6, pp. 697-712, 06/01/1976
Copyright © 1976 by The Histochemical Society


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The Journal of Histochemistry & Cytochemistry is owned, published, and licensed by The Histochemical Society © 1976