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Chromium concentration by proximal renal tubule cells: an ultrastructural, microanalytical and cytochemical study

JP Berry, J Hourdry, P Galle and G Lagrue

After treating rats with potassium bichromate, x-ray microanalysis of the proximal renal tubule cells demonstrated the presence of chromium in intracellular vacuoles. The lysosomal nature of these vacuoles is shown by the visualization of acid phosphatase activity. Chromium is concentrated both in the autolytic vacuoles and in their residual forms. The metal is eliminated quite late, concomitant with cellular necrosis.

Volume 26, Issue 8, pp. 651-657, 08/01/1978
Copyright © 1978 by The Histochemical Society


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Home page
 Hum Exp ToxicolHome page
J.P. Berry, R. Masse, F. Escaig, and P. Galle
Intracellular Localization of Cerium. A Microanalytical Study using an Electron Microprobe and Ionic Microanalysis
Human and Experimental Toxicology, November 1, 1989; 8(6): 511 - 520.
[Abstract] [PDF]



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