|
|
|
|
 |
|||
|
|||
Immunohistochemical localization of carbonic anhydrase isoenzyme C in the central and peripheral nervous system of the mouse
T Kumpulainen and LK Korhonen
The regional and cellular distribution of the high activity carbonic anhydrase isoenzyme (CA C or CA II) in the mouse nervous system was investigated by an indirect immunoperoxidase (peroxidase- antiperoxidase) method using cross-reactive antibodies prepared against human CA C. In the mature brain an overall strong CA C specific reactivity was revealed in the heavily myelinated nerve tracts, the main immunostaining originating from small, intensively reacting cells interpreted as oligodendrocytes and from the myelin sheaths. An obvious straining was also revealed in the choroid plexus cells, especially in their free borders, and in the erythrocytes of the blood vessels, while the glial cells of the retina similarly exhibited a strong reaction. In the developing brain, CA C was absent shortly after birth, but achieved almost the mature pattern of distribution within about 3 weeks. In the spinal cord most of the positive cells were found in the grey matter, their processes projecting towards the white matter. No reaction was obtained in the sciatic nerve fibers or in the neuronal or satellite cells of the coeliac ganglion.
Volume 30,
Issue 4,
pp. 283-292,
04/01/1982
Copyright © 1982 by The Histochemical Society
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  P. Pan, M. Leppilampi, S. Pastorekova, J. Pastorek, A. Waheed, W. S. Sly, and S. Parkkila Carbonic anhydrase gene expression in CA II-deficient (Car2-/-) and CA IX-deficient (Car9-/-) mice J. Physiol., March 1, 2006; 571(2): 319 - 327. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. Jalabi, N. Boehm, D. Grucker, and M. S. Ghandour Recovery of Myelin after Induction of Oligodendrocyte Cell Death in Postnatal Brain J. Neurosci., March 16, 2005; 25(11): 2885 - 2894. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Lehtonen, B. Shen, M. Vihinen, A. Casini, A. Scozzafava, C. T. Supuran, A.-K. Parkkila, J. Saarnio, A. J. Kivela, A. Waheed, et al. Characterization of CA XIII, a Novel Member of the Carbonic Anhydrase Isozyme Family J. Biol. Chem., January 23, 2004; 279(4): 2719 - 2727. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Parkkila, A.-K. Parkkila, H. Rajaniemi, G. N. Shah, J. H. Grubb, A. Waheed, and W. S. Sly Expression of membrane-associated carbonic anhydrase XIV on neurons and axons in mouse and human brain PNAS, February 13, 2001; 98(4): 1918 - 1923. [Abstract] [Full Text] [PDF]
|
|
| Guidelines | Subscriptions | About | exPRESS - Current - Archive | Business Information | Contact |