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Lanthanide chelates as new fluorochrome labels for cytochemistry

EJ Soini, LJ Pelliniemi, IA Hemmila, VM Mukkala, JJ Kankare and K Frojdman

Wallac Oy, Turku, Finland.

Anti-rabbit IgG labeled with a new fluorescent europium chelate was used to localize rabbit IgG to human smooth muscle myosin in a histological section. The antibody labeled with the europium chelate could be viewed with a conventional fluorescence microscope with a steady-state light source. This result encourages the development of a time-resolved fluorescence microscope, because a significant improvement in the signal-to-noise ratio can be anticipated.

Volume 36, Issue 11, pp. 1449-1451, 11/01/1988
Copyright © 1988 by The Histochemical Society


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The Journal of Histochemistry & Cytochemistry is owned, published, and licensed by The Histochemical Society © 1988