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Localization of prolactin-like immunoreactivity in grafted human sweat glands

MT Robertson, HR Alho and AA Martin

Department of Pediatrics, Georgetown University, Washington, DC 20007.

Using a double-antibody immunoperoxidase technique, we demonstrated human prolactin-like material in some cells of the secretory coil and in luminal duct cells of sweat glands of human skin which had been carried as grafts on mice for 32-35 weeks. It therefore seems likely that a population of cells in the secretory coil synthesizes prolactin and can be considered as diffuse peripheral endocrine cells. The prolactin may function locally to regulate sweat electrolyte concentration.

Volume 37, Issue 5, pp. 625-628, 05/01/1989
Copyright © 1989 by The Histochemical Society


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