Journal of Histochemistry and Cytochemistry Priciples for Free Access to Science
  Search:   
    >> Advanced Search

Guidelines | Subscriptions | About | exPRESS - Current - Archive | Business Information | Contact
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Carter, D. H.
Right arrow Articles by Aaron, J. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Carter, D. H.
Right arrow Articles by Aaron, J. E.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Immunolocalization of collagen types I and III, tenascin, and fibronectin in intramembranous bone

DH Carter, P Sloan and JE Aaron

Department of Oral Medicine, University of Manchester, Turner Dental School, United Kingdom.

Structural components of the organic bone matrix were located by immunohistochemical techniques in fresh-frozen sections of normal and dysplastic bone. Fine and coarse birefringent fibers were identified as separate and distinctive features in the extracellular matrix by antibodies raised against human collagen Type III. The glycoprotein tenascin was located on a proportion of the fibers in a characteristic beaded pattern, which was absent in dysplastic bone. The fibers originated in the periosteum or in the fibrous stroma of the marrow cavity and were oriented with regard to both the spatial and the lamellar organization of the bone. The disposition and composition of the fibers suggests that they form a preliminary framework on which intramembranous bone modeling proceeds, and that the specific location of tenascin on the fibers in normal developing membrane bone may be important in determining the alignment of the bone tissue. Epitopes recognized by the collagen Type I and fibronectin antibodies were demonstrated throughout the mineralized matrix, but their incorporation into the collagen "Type III" fibers was evident only outside the mineralized matrix.

Volume 39, Issue 5, pp. 599-606, 05/01/1991
Copyright © 1991 by The Histochemical Society


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 Clin. Chem.Home page
K. Stoffel, H. Engler, M. Kuster, and W. Riesen
Changes in Biochemical Markers after Lower Limb Fractures
Clin. Chem., January 1, 2007; 53(1): 131 - 134.
[Abstract] [Full Text] [PDF]

Home page
 JDRHome page
D.D. Bosshardt
Are Cementoblasts a Subpopulation of Osteoblasts or a Unique Phenotype?
Journal of Dental Research, May 1, 2005; 84(5): 390 - 406.
[Abstract] [Full Text] [PDF]

Home page
 Br. J. Ophthalmol.Home page
J. Albon, W. S S Karwatowski, D. L Easty, T. J Sims, and V. C Duance
Age related changes in the non-collagenous components of the extracellular matrix of the human lamina cribrosa
Br. J. Ophthalmol., March 1, 2000; 84(3): 311 - 317.
[Abstract] [Full Text]

Home page
 Ann Rheum DisHome page
Y. T Konttinen, T.-F. Li, O. Michelsson, J.-W. Xu, T. Sorsa, S. Santavirta, S. Imai, and I. Virtanen
Expression of tenascin-C in aseptic loosening of total hip replacement
Ann Rheum Dis, October 1, 1998; 57(10): 619 - 623.
[Abstract] [Full Text]



Guidelines | Subscriptions | About | exPRESS - Current - Archive | Business Information | Contact
The Journal of Histochemistry & Cytochemistry is owned, published, and licensed by The Histochemical Society © 1991