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HISTOCHEMICAL DEMONSTRATION OF AMINOPEPTIDASE

M. S. BURSTONE 1 and J. E. FOLK 2

1 National Institute of Dental Research, National Institutes of Health, Bethesda 14, Maryland.
2 Research Associate, American Dental Association, at the National Institute of Dental Research.

A histochemical method for demonstration of aminopeptidase in tissue sections using the substrates l-leucyl beta-naphthylamide and dl-alanyl beta-naphthylamide is presented. The method may also be quantitated on tissue sections.

The successful histochemical demonstration of the enzyme with both substrates is dependent upon the use of frozen-dried tissues.

Submitted on September 13, 1955


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