Journal of Histochemistry and Cytochemistry Priciples for Free Access to Science
  Search:   
    >> Advanced Search

Guidelines | Subscriptions | About | exPRESS - Current - Archive | Business Information | Contact
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Akiyama, J.
Right arrow Articles by Hawgood, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Akiyama, J.
Right arrow Articles by Hawgood, S.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
Journal of Histochemistry and Cytochemistry, Vol. 50, 993-996, July 2002, Copyright © 2002, The Histochemical Society, Inc.

BRIEF REPORT

Tissue Distribution of Surfactant Proteins A and D in the Mouse

Jennifer Akiyamaa, Ari Hoffmana, Cynthia Browna, Lennell Allena, Jess Edmondsona, Francis Poulaina, and Samuel Hawgooda
a Departments of Pediatrics and Cardiovascular Research Institute, University of California San Francisco, San Francisco, California

Correspondence to: Samuel Hawgood, Suite 150, U. of California San Francisco, Laurel Heights Campus, 3333 California Street, San Francisco, CA 94118-1245. E-mail: hawgood@itsa.ucsf.edu

Surfactant proteins A and D, collagen-like lectins (collectins), were first isolated from the lung. In the lung, SP-A and SP-D have roles in surfactant homeostasis and innate immunity. In this study we show that SP-A and SP-D mRNA can be detected in a significant number of non-pulmonary tissues but the proteins have a more limited distribution. SP-D protein was detected in lung, uterus, ovary, and lacrimal gland, whereas SP-A protein was detected only in the lung. The results suggest that SP-D participates in mucosal immunity throughout the body. (J Histochem Cytochem 50:993–996, 2002)

Key Words: surfactant proteins, collectins, innate immunity


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 Biol. Reprod.Home page
I. Garcia-Verdugo, Z. Tanfin, E. Dallot, M.-J. Leroy, and M. Breuiller-Fouche
Surfactant Protein A Signaling Pathways in Human Uterine Smooth Muscle Cells
Biol Reprod, August 1, 2008; 79(2): 348 - 355.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
G. D. Snyder, R. E. Oberley-Deegan, K. L. Goss, S. A. Romig-Martin, L. L. Stoll, J. M. Snyder, and N. L. Weintraub
Surfactant protein D is expressed and modulates inflammatory responses in human coronary artery smooth muscle cells
Am J Physiol Heart Circ Physiol, May 1, 2008; 294(5): H2053 - H2059.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
C. L. S. George, K. L. Goss, D. K. Meyerholz, F. S. Lamb, and J. M. Snyder
Surfactant-Associated Protein A Provides Critical Immunoprotection in Neonatal Mice
Infect. Immun., January 1, 2008; 76(1): 380 - 390.
[Abstract] [Full Text] [PDF]

Home page
 Mol Hum ReprodHome page
R. E. Oberley, K. L. Goss, D. S. Hoffmann, K. A. Ault, T. L. Neff, K. H. Ramsey, and J. M. Snyder
Regulation of surfactant protein D in the mouse female reproductive tract in vivo
Mol. Hum. Reprod., December 1, 2007; 13(12): 863 - 868.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
L. Brauer, C. Kindler, K. Jager, S. Sel, B. Nolle, U. Pleyer, M. Ochs, and F. P. Paulsen
Detection of Surfactant Proteins A and D in Human Tear Fluid and the Human Lacrimal System
Invest. Ophthalmol. Vis. Sci., September 1, 2007; 48(9): 3945 - 3953.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
I. Garcia-Verdugo, D. Leiber, P. Robin, E. Billon-Denis, R. Chaby, and Z. Tanfin
Direct Interaction of Surfactant Protein A with Myometrial Binding Sites: Signaling and Modulation by Bacterial Lipopolysaccharide
Biol Reprod, April 1, 2007; 76(4): 681 - 691.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
S. Kunzmann, J. R. Wright, W. Steinhilber, B. W. Kramer, K. Blaser, C. P. Speer, and C. Schmidt-Weber
TGF-beta1 in SP-A preparations influence immune suppressive properties of SP-A on human CD4+ T lymphocytes
Am J Physiol Lung Cell Mol Physiol, October 1, 2006; 291(4): L747 - L756.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
X. Xu, D. Zhang, N. Lyubynska, P. J. Wolters, N. P. Killeen, P. Baluk, D. M. McDonald, S. Hawgood, and G. H. Caughey
Mast Cells Protect Mice from Mycoplasma Pneumonia
Am. J. Respir. Crit. Care Med., January 15, 2006; 173(2): 219 - 225.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
J. Casey, J. Kaplan, E. N. Atochina-Vasserman, A. J. Gow, H. Kadire, Y. Tomer, J. H. Fisher, S. Hawgood, R. C. Savani, and M. F. Beers
Alveolar Surfactant Protein D Content Modulates Bleomycin-induced Lung Injury
Am. J. Respir. Crit. Care Med., October 1, 2005; 172(7): 869 - 877.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
M. Ni, D. J. Evans, S. Hawgood, E. M. Anders, R. A. Sack, and S. M. J. Fleiszig
Surfactant Protein D Is Present in Human Tear Fluid and the Cornea and Inhibits Epithelial Cell Invasion by Pseudomonas aeruginosa
Infect. Immun., April 1, 2005; 73(4): 2147 - 2156.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Cell Mol. Bio.Home page
C. Coraux, B. Nawrocki-Raby, J. Hinnrasky, C. Kileztky, D. Gaillard, C. Dani, and E. Puchelle
Embryonic Stem Cells Generate Airway Epithelial Tissue
Am. J. Respir. Cell Mol. Biol., February 1, 2005; 32(2): 87 - 92.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
R. Leth-Larsen, P. Garred, H. Jensenius, J. Meschi, K. Hartshorn, J. Madsen, I. Tornoe, H. O. Madsen, G. Sorensen, E. Crouch, et al.
A Common Polymorphism in the SFTPD Gene Influences Assembly, Function, and Concentration of Surfactant Protein D
J. Immunol., February 1, 2005; 174(3): 1532 - 1538.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
M. A. Crane-Godreau and C. R. Wira
CCL20/Macrophage Inflammatory Protein 3{alpha} and Tumor Necrosis Factor Alpha Production by Primary Uterine Epithelial Cells in Response to Treatment with Lipopolysaccharide or Pam3Cys
Infect. Immun., January 1, 2005; 73(1): 476 - 484.
[Abstract] [Full Text] [PDF]

Home page
 Mol Hum ReprodHome page
R. Leth-Larsen, C. Floridon, O. Nielsen, and U. Holmskov
Surfactant protein D in the female genital tract
Mol. Hum. Reprod., March 1, 2004; 10(3): 149 - 154.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Cell Mol. Bio.Home page
J. Madsen, I. Tornoe, O. Nielsen, C. Koch, W. Steinhilber, and U. Holmskov
Expression and Localization of Lung Surfactant Protein A in Human Tissues
Am. J. Respir. Cell Mol. Biol., November 1, 2003; 29(5): 591 - 597.
[Abstract] [Full Text]

Home page
 Cancer Res.Home page
F. Zhang, W. Pao, S. M. Umphress, S. B. Jakowlew, A. M. Meyer, L. D. Dwyer-Nield, L. D. Nielsen, K. Takeda, E. W. Gelfand, J. H. Fisher, et al.
Serum Levels of Surfactant Protein D Are Increased in Mice with Lung Tumors
Cancer Res., September 15, 2003; 63(18): 5889 - 5894.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Lung Cell. Mol. Physiol.Home page
I. Y. Haddad, C. Milla, S. Yang, A. Panoskaltsis-Mortari, S. Hawgood, D. L. Lacey, and B. R. Blazar
Surfactant protein A is a required mediator of keratinocyte growth factor after experimental marrow transplantation
Am J Physiol Lung Cell Mol Physiol, September 1, 2003; 285(3): L602 - L610.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
S. Wagner, N. J. Lynch, W. Walter, W. J. Schwaeble, and M. Loos
Differential Expression of the Murine Mannose-Binding Lectins A and C in Lymphoid and Nonlymphoid Organs and Tissues
J. Immunol., February 1, 2003; 170(3): 1462 - 1465.
[Abstract] [Full Text] [PDF]



Guidelines | Subscriptions | About | exPRESS - Current - Archive | Business Information | Contact
The Journal of Histochemistry & Cytochemistry is owned, published, and licensed by The Histochemical Society © 2002