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STUDIES ON STREPTOCOCCAL HYALURONIDASE AND ANTIHYALURONIDASE. III. THE PRODUCTION AND CELLULAR LOCALIZATION OF HYALURONIDASE FOLLOWING STREPTOCOCCAL INFECTION

E. W. EMMART 1 and W. A. TURNER JR. 1

1 Laboratory of Pharmacology and Toxicology, N. I. A. M. D., National Institutes of Health, Bethesda 14, Maryland

I. Streptococcal hyaluronidase and the bacterium Streptococcus hemolyticus, Group C, strain 7, have been identified within the same tissue section by tagging the former with its specific antibody coupled to yellow-green fluorescein and the latter with Group C antisera coupled to acid rhodamine B (C.I. No. 45100).

2. The methods used above suggest a means of studying the absorption and activity of other antigenic enzymes and toxins elaborated during the course of infection.

Submitted on November 24, 1959


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